Hormone Replacement Therapy

The most well-known women’s sex hormones are estrogen, progesterone, and testosterone.

When there is a disruption in these or any other hormones in the body, a cascade of health problems can ensue. At PRIME Medicine, we will focus on your needs, as a woman, and help treat the source of any symptoms you are experiencing.

When any of these hormones are out of balance, it is important to return them to homeostasis.

Estrogen is predominantly produced in the ovaries, but small amounts come from the adrenal glands and fat cells, as well as the placenta during pregnancy. Estrogen is vital for puberty, menstruation, pregnancy, and menopause. It also affects the brain, skin, hair, urinary tract, cardiovascular system, and musculoskeletal system.

Progesterone is produced in the ovaries after ovulation and is also made by the placenta during pregnancy. Although its role is more specialized to aid in the menstrual cycle, it is a crucial hormone, and imbalance can affect uterine lining, pregnancy, and estrogen production after ovulation.

Although testosterone is considered a male hormone, it still plays a small but vital role in women’s health and is produced in tiny amounts in the adrenal glands and ovaries. It is an essential hormone for libido, regulation of menstrual cycles, as well as bone and muscle strength.

When any of these hormones are out of balance, it is important to return them to homeostasis. Women’s needs for each of these hormones fluctuate throughout life due to puberty, pregnancy, breastfeeding, and even throughout the menstrual cycle each month. As menopause approaches, hormone production in the ovaries begins to slow down – estrogen begins to fluctuate more, and progesterone levels steadily decline. This typically happens around the age of 50 but can vary widely between individuals.

Symptoms of hormone imbalances can include:

●Decreased sexual desire

●Vaginal dryness or painful intercourse

●Irregular menstrual cycles and skipped periods

●Infertility

●Pelvic pain

●Increased or reduced hair growth

●Depression

●Prolonged symptoms of menopause

●Morning sickness or other pregnancy-like symptoms

Bioidentical Hormone Replacement Therapy (BHRT)

To combat hormone imbalances, we offer bioidentical hormone replacement therapy (BHRT), which replaces the missing hormones with those that are biologically identical to them. Your body is less likely to have an adverse reaction to them since they are otherwise indistinguishable from those your body already produces.

BHRT comes in several different forms, and at PRIME Medicine, we carefully take into consideration your symptoms, medical conditions, and history before making a recommendation for a specific treatment. Options may include:

BioTE® pellet therapy
Compounded natural hormones
Nutraceutical supplementation

Delivery of BHRT depends mainly on the specific therapy option, but include:

Implanted pellets
Creams
Patches
Gels
Injections

BioTE® pellet therapy
Compounded natural hormones
Nutraceutical supplementation

Delivery of BHRT depends mainly on the specific therapy option, but include:

Implanted pellets
Creams
Patches
Gels
Injections

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What Is PRIME Medicine™?

Every PRIME Medicine patient receives the following:

In Depth Testing

Uncover the full picture of your health with our advanced lab testing that covers hormones, vitamins, metabolic markers, genetics, food allergies, and more.

A PRIME 360 Complete Health Plan™

Our doctors will create a personalized plan based off of your labs, symptoms, and goals. We will then match the best of natural and modern medicine to your health needs.

Customized treatment protocol

We create custom IV, supplement, and medication solutions for you based on your bloodwork + health plan and offer it to you in the clinic or delivered to your door.

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The PRIME Process.

Our 4 step process is designed to be as convenient and

effective as possible.

The 4 Steps

One

Schedule 1-on-1 Session With A PRIME Health Coach

Do a quick phone call with your health coach to discuss your symptoms and goals so they can get started with your personalized health plan.

Two

Get Personalized Diagnostic Lab Work

We do all of our lab work in our beautiful clinic in Corona Del Mar. Results arrive within 5 days. You’ll get a comprehensive review in the next step.

Three

Receive & Review Your PRIME 360 Complete Health Plan From Your Doctor

One of our Integrative Medical Doctors will meet with you either in clinic or telehealth (whatever is best for you) to discuss your lab work and go over your health plan with you.

Four

We’ll Create Your Personalized Med Packs And You’ll Start Your Protocol

Once you’ve reviewed your health plan (covering lifestyle, supplement, medication, and other treatment recommendations) you’ll be able to receive your “Med Packs” either in-clinic or shipped right to your door.

You will also have monthly check-ins with your PRIME Health Coach for continued support.

Our expert process.

Our 4 step process is designed to be as convenient and effective as possible. Allow one of our world class integrative doctors to give you the gift of good health.

The 4 Steps

One

Schedule 1-on-1 Intake With Prime Health Coach

Do a quick phone call with your health coach to discuss your symptoms and goals so they can get started with your personalized health plan.

Two

Get Personalized Diagnostic Lab Work

We do all of our lab work in our beautiful clinic in Corona Del Mar. Results arrive within X days. You’ll get a comprehensive review in the next step.

Three

Receive & Review Your Prime 360 Complete Health Plan From Your Doctor

One of our Integrative Medical Doctors will meet with you either in clinic or telehealth (whatever is best for you) to discuss your lab work and go over your health plan with you.

Four

We’ll Create Your Personalized Med Packs And You’ll Start Your Protocol

Once you’ve reviewed your health plan (covering lifestyle, supplement, medication, and other treatment recommendations) you’ll be able to receive your “Med Packs” either in-clinic or shipped right to your door.

You will also have monthly check-ins with your Prime Health Coach for continued support.

People Love PRIME Medicine… And We’re Just Getting Started

We can keep telling you why PRIME Personalized Medicine

is the future of medicine but it’s probably best if you hear

it from our raving fans instead.

Thais S.

Feb 16, 2025

"Finally found a doctor who actually cares about helping people stay as healthy as possible.

Aaron W.

Sep 26, 2024

"This group of doctors takes the extra effort to help you do it right and is invested in the outcome."

Sammy M.

Oct 13, 2023

"I Recommend everyone, whether healthy or not, to pay a visit to this clinic to optimize your health!"

Reem M.

Oct 10, 2023

"Their knowledge and approach to naturopathic medicine made all the difference."

Frequently Asked Questions

Do you take insurance?

No, we do not take insurance as they don't typically cover alternative/preventative/functional medicine. But we can send you a superbill and you can submit it to your insurance to see if they will cover it.

Do all of your providers specialize in the same thing?

Yes, all providers are trained to create a PRIME Health Plan in the same way, but each plan is unique to the needs of the patient. So all of our providers are similar in that way. Each provider may also have unique specialities. Typically a patient will come in, receive a PRIME Health Plan and after they're comfortable with how the clinic works they may utilize the advanced services of any provider but the doctor who created their initial health plan will remain their primary provider at PRIME.

What’s your new patient process?

Step 1: Fill out your intake form

Step 2: Schedule your blood work at home (extra fee) or in clinic. You do not need to go to Quest or Labcorp which can be inconvenient and frustrating.

Step 3: Do your Initial Visit and receive your PRIME Health Plan.

Step 4: Get any personalized supplements, peptides, medications right from the clinic (if needed).

Step 5: Continue on your healing journey with support from our doctors, nurses, and medical assistants as needed.

Can I request a specific provider?

You're welcome to ask for a specific provider and we will do our best to accommodate, however since each provider is trained to create a PRIME Health Plan in the same way, and since we heavily vet our providers, you can be confident with any doctor here at PRIME. We recommend that you start sooner with whoever has an opening vs waiting for a certain provider, since our goal is to help get you as healthy as possible as soon as possible.

What initial blood work do you typically do?

Our blood tests go deeper than what you'd typically get from your primary care doctor or any doctor that takes insurance. If you've done lab work within the last year we can use it, but we may need to order anything that is missing so that your doctor here can fully address your needs. Please call us if you have any further questions.

How do you handle blood work?

We are able to do blood draws in our clinic making it very convenient for our patients. We also offer at home blood draws if needed. Your doctor will help you decide which testing is best for your specific scenario. They typically ask a patient to do a little more testing up front until we get your treatment plan dialed in and then you can move into "cruise control" with less testing less frequently as long as you're healthy and feeling good. We can use your blood work from another provider as long as it is less than 1 year old.

Do you guys do peptide therapy?

Yes. We source the highest quality clinical grade peptides and have been offering peptide therapy for a long time (before it was popular.) Our doctors are highly experienced and will help you enjoy the benefits of peptides in a safe way that is personalized to you.